Chapter 9 | The Immune System

  1. Different MHC I molecules between donor and recipient cells can lead to rejection of a transplanted organ or tissue. Suggest a reason for this.
  2. If a series of genetic mutations prevented some, but not all, of the complement proteins from binding antibodies or pathogens, would the entire complement system be compromised?
  3. Explain the difference between an epitope and an antigen.
  4. What is a naïve B or T cell?
  5. How does the TH1 response differ from the TH2 response?
  6. In mammalian adaptive immune systems, T cell receptors are extraordinarily diverse. What function of the immune system results from this diversity, and how is this diversity achieved?
  7. How do B and T cells differ with respect to antigens that they bind?
  8. Why is the immune response after reinfection much faster than the adaptive immune response after the initial infection?
  9. What are the benefits and costs of antibody cross reactivity?

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