Chapter 2 | The Chemical Foundation of Life

acid molecule that donates hydrogen ions and increases the concentration of hydrogen ions in a solution

adhesion attraction between water molecules and other molecules

aliphatic hydrocarbon hydrocarbon consisting of a linear chain of carbon atoms

alpha-helix structure (α-helix) type of secondary structure of proteins formed by folding of the polypeptide into a helix shape with hydrogen bonds stabilizing the structure

amino acid monomer of a protein; has a central carbon or alpha carbon to which an amino group, a carboxyl group, a hydrogen, and an R group or side chain is attached; the R group is different for all 20 amino acids

anion negative ion that is formed by an atom gaining one or more electrons

aromatic hydrocarbon hydrocarbon consisting of closed rings of carbon atoms

atom the smallest unit of matter that retains all of the chemical properties of an element

atomic mass calculated mean of the mass number for an element’s isotopes

atomic number total number of protons in an atom

balanced chemical equation statement of a chemical reaction with the number of each type of atom equalized for both the products and reactants

base molecule that donates hydroxide ions or otherwise binds excess hydrogen ions and decreases the concentration of hydrogen ions in a solution

beta-pleated sheet (β-pleated) secondary structure found in proteins in which “pleats” are formed by hydrogen bonding between atoms on the backbone of the polypeptide chain

biological macromolecule large molecule necessary for life that is built from smaller organic molecules buffer substance that prevents a change in pH by absorbing or releasing hydrogen or hydroxide ions calorie amount of heat required to change the temperature of one gram of water by one degree Celsius

capillary action occurs because water molecules are attracted to charges on the inner surfaces of narrow tubular structures such as glass tubes, drawing the water molecules to the sides of the tubes

carbohydrate biological macromolecule in which the ratio of carbon to hydrogen and to oxygen is 1:2:1; carbohydrates serve as energy sources and structural support in cells and form the a cellular exoskeleton of arthropods

cation positive ion that is formed by an atom losing one or more electrons

cellulose polysaccharide that makes up the cell wall of plants; provides structural support to the cell

chaperone (also, chaperonin) protein that helps nascent protein in the folding process

chemical bond interaction between two or more of the same or different atoms that results in the formation of molecules

chemical reaction process leading to the rearrangement of atoms in molecules

chemical reactivity the ability to combine and to chemically bond with each other

chitin type of carbohydrate that forms the outer skeleton of all arthropods that include crustaceans and insects; it also forms the cell walls of fungi

cohesion intermolecular forces between water molecules caused by the polar nature of water; responsible for surface tension

compound substance composed of molecules consisting of atoms of at least two different elements

covalent bond type of strong bond formed between two of the same or different elements; forms when electrons are shared between atoms

dehydration synthesis (also, condensation) reaction that links monomer molecules together, releasing a molecule of water for each bond formed

denaturation loss of shape in a protein as a result of changes in temperature, pH, or exposure to chemicals

deoxyribonucleic acid (DNA) double-helical molecule that carries the hereditary information of the cell

disaccharide two sugar monomers that are linked together by a glycosidic bond

dissociation release of an ion from a molecule such that the original molecule now consists of an ion and the charged remains of the original, such as when water dissociates into H+ and OH-

electrolyte ion necessary for nerve impulse conduction, muscle contractions and water balance

electron negatively charged subatomic particle that resides outside of the nucleus in the electron orbital; lacks functional mass and has a negative charge of –1 unit

electron configuration arrangement of electrons in an atom’s electron shell (for example, 1s22s22p6)

electron orbital how electrons are spatially distributed surrounding the nucleus; the area where an electron is most likely to be found

electron transfer movement of electrons from one element to another; important in creation of ionic bonds

electronegativity ability of some elements to attract electrons (often of hydrogen atoms), acquiring partial negative charges in molecules and creating partial positive charges on the hydrogen atoms

element one of 118 unique substances that cannot be broken down into smaller substances; each element has unique properties and a specified number of protons

enantiomers molecules that share overall structure and bonding patterns, but differ in how the atoms are three dimensionally placed such that they are mirror images of each other

enzyme catalyst in a biochemical reaction that is usually a complex or conjugated protein

equilibrium steady state of relative reactant and product concentration in reversible chemical reactions in a closed system

evaporation separation of individual molecules from the surface of a body of water, leaves of a plant, or the skin of an organism

functional group group of atoms that provides or imparts a specific function to a carbon skeleton

geometric isomer isomer with similar bonding patterns differing in the placement of atoms alongside a double covalent bond

glycogen storage carbohydrate in animals

glycosidic bond bond formed by a dehydration reaction between two monosaccharides with the elimination of a water molecule

heat of vaporization of water high amount of energy required for liquid water to turn into water vapor

hormone chemical signaling molecule, usually protein or steroid, secreted by endocrine cells that act to control or regulate specific physiological processes

hydrocarbon molecule that consists only of carbon and hydrogen

hydrogen bond weak bond between slightly positively charged hydrogen atoms to slightly negatively charged atoms in other molecules

hydrolysis reaction causes breakdown of larger molecules into smaller molecules with the utilization of water

hydrophilic describes ions or polar molecules that interact well with other polar molecules such as water

hydrophobic describes uncharged non-polar molecules that do not interact well with polar molecules such as water

inert gas (also, noble gas) element with filled outer electron shell that is unreactive with other atoms

ion atom or chemical group that does not contain equal numbers of protons and electrons

ionic bond chemical bond that forms between ions with opposite charges (cations and anions)

irreversible chemical reaction chemical reaction where reactants proceed uni-directionally to form products

isomers molecules that differ from one another even though they share the same chemical formula

isotope one or more forms of an element that have different numbers of neutrons

law of mass action chemical law stating that the rate of a reaction is proportional to the concentration of the reacting substances

lipid macromolecule that is nonpolar and insoluble in water

litmus paper (also, pH paper) filter paper that has been treated with a natural water-soluble dye that changes its color as the pH of the environment changes so it can be used as a pH indicator

mass number total number of protons and neutrons in an atom

matter anything that has mass and occupies space

messenger RNA (mRNA) RNA that carries information from DNA to ribosomes during protein synthesis

molecule two or more atoms chemically bonded together

monomer smallest unit of larger molecules called polymers

monosaccharide single unit or monomer of carbohydrates

neutron uncharged particle that resides in the nucleus of an atom; has a mass of one amu

noble gas see inert gas

nonpolar covalent bond type of covalent bond that forms between atoms when electrons are shared equally between them

nucleic acid biological macromolecule that carries the genetic blueprint of a cell and carries instructions for the functioning of the cell

nucleotide monomer of nucleic acids; contains a pentose sugar, one or more phosphate groups, and a nitrogenous base

nucleus core of an atom; contains protons and neutrons

octet rule rule that atoms are most stable when they hold eight electrons in their outermost shells

omega fat type of polyunsaturated fat that is required by the body; the numbering of the carbon omega starts from the methyl end or the end that is farthest from the carboxylic end

orbital region surrounding the nucleus; contains electrons

organic molecule any molecule containing carbon (except carbon dioxide)

peptide bond bond formed between two amino acids by a dehydration reaction

periodic table organizational chart of elements indicating the atomic number and atomic mass of each element; provides key information about the properties of the elements

pH paper see litmus paper

pH scale scale ranging from zero to 14 that is inversely proportional to the concentration of hydrogen ions in a solution

phosphodiester linkage covalent chemical bond that holds together the polynucleotide chains with a phosphate group linking two pentose sugars of neighboring nucleotides

phospholipid major constituent of the membranes; composed of two fatty acids and a phosphate-containing group attached to a glycerol backbone

polar covalent bond type of covalent bond that forms as a result of unequal sharing of electrons, resulting in the creation of slightly positive and slightly negative charged regions of the molecule

polymer chain of monomer residues that is linked by covalent bonds; polymerization is the process of polymer formation from monomers by condensation

polynucleotide long chain of nucleotides

polypeptide long chain of amino acids linked by peptide bonds

polysaccharide long chain of monosaccharides; may be branched or unbranched

primary structure linear sequence of amino acids in a protein

product molecule found on the right side of a chemical equation

protein biological macromolecule composed of one or more chains of amino acids

proton positively charged particle that resides in the nucleus of an atom; has a mass of one amu and a charge of +1

purine type of nitrogenous base in DNA and RNA; adenine and guanine are purines

pyrimidine type of nitrogenous base in DNA and RNA; cytosine, thymine, and uracil are pyrimidines

quaternary structure association of discrete polypeptide subunits in a protein

radioisotope isotope that emits radiation composed of subatomic particles to form more stable elements

reactant molecule found on the left side of a chemical equation

reversible chemical reaction chemical reaction that functions bi-directionally, where products may turn into reactants if their concentration is great enough

ribonucleic acid (RNA) single-stranded, often internally base paired, molecule that is involved in protein synthesis

ribosomal RNA (rRNA) RNA that ensures the proper alignment of the mRNA and the ribosomes during protein synthesis and catalyzes the formation of the peptide linkage

saturated fatty acid long-chain of hydrocarbon with single covalent bonds in the carbon chain; the number of hydrogen atoms attached to the carbon skeleton is maximized

secondary structure regular structure formed by proteins by intramolecular hydrogen bonding between the oxygen atom of one amino acid residue and the hydrogen attached to the nitrogen atom of another amino acid residue

solvent substance capable of dissolving another substance

specific heat capacity the amount of heat one gram of a substance must absorb or lose to change its temperature by one degree Celsius

sphere of hydration when a polar water molecule surrounds charged or polar molecules thus keeping them dissolved and in solution

starch storage carbohydrate in plants

steroid type of lipid composed of four fused hydrocarbon rings forming a planar structure

structural isomers molecules that share a chemical formula but differ in the placement of their chemical bonds

substituted hydrocarbon hydrocarbon chain or ring containing an atom of another element in place of one of the backbone carbons

surface tension tension at the surface of a body of liquid that prevents the molecules from separating; created by the attractive cohesive forces between the molecules of the liquid

tertiary structure three-dimensional conformation of a protein, including interactions between secondary structural elements; formed from interactions between amino acid side chains

trans fat fat formed artificially by hydrogenating oils, leading to a different arrangement of double bond(s) than those found in naturally occurring lipids

transcription process through which messenger RNA forms on a template of DNA

transfer RNA (tRNA) RNA that carries activated amino acids to the site of protein synthesis on the ribosome

translation process through which RNA directs the formation of protein

triacylglycerol (also, triglyceride) fat molecule; consists of three fatty acids linked to a glycerol molecule

unsaturated fatty acid long-chain hydrocarbon that has one or more double bonds in the hydrocarbon chain

valence shell outermost shell of an atom

van der Waals interaction very weak interaction between molecules due to temporary charges attracting atoms that are very close together

wax lipid made of a long-chain fatty acid that is esterified to a long-chain alcohol; serves as a protective coating on some feathers, aquatic mammal fur, and leaves

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